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Flux control analysis of eight reactions involved in oxidative phosphorylation of mitochondria from rat quadriceps muscle was performed under circumstances resembling in vivo conditions of carbohydrate or fatty acid oxidation. The major flux control at a respiration rate of 55% of state 3 was associated with the ADP-generating system, i.e., 0.58 ± 0.05 with pyruvate, but significantly lower, 0.40 ± 0...
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