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Butyrate‐producing bacteria play a key role in human health, and recent studies have triggered interest in their development as next‐generation probiotics. However, there remains limited knowledge not only on the identification of high‐butyrate‐producing bacteria in the human gut but also in the metabolic capacities for prebiotic carbohydrates and their interaction with the host. Herein, it was discovered...
The commensal gut bacterium Akkermansia muciniphila is well known as a promising probiotic candidate that improves host health and prevents diseases. However, the biological interaction of A. muciniphila with human gut epithelial cells has rarely been explored for use in biotherapeutics. Here, we developed an in vitro device that simulates the gut epithelium to elucidate the biological effects of...
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