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Parkinson's disease (PD), a chronic and progressive neurodegenerative disease, can reduce the population of dopaminergic neurons in the substantia nigra. The cause of this neuronal death remains unclear. 1‐Methyl‐4‐phenylpyridinium ion (MPP+) is a potent neurotoxin that can destroy dopaminergic (DA) neurons and promote PD. Garcinol, a polyisoprenylated benzophenone derivative, was extracted from Garcinia indica...
In recent years, neuropathological and epidemiological studies have indicated an association between Alzheimer's disease (AD) and several cardiovascular risk factors. In this study, the cardio‐protective effects of folic acid (FA) in early stage AD was elucidated using a triple‐transgenic (3xTg) Alzheimer's mouse model. Eleven‐month‐old C57BL/6 mice and 3xTg mice were assigned to five groups. During...
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