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GDF11 modulates embryonic patterning and kidney organogenesis. Herein, we sought to define GDF11 function in the adult kidney and in renal diseases. In vitro renal cell lines, genetic, and murine in vivo renal injury models were examined. Among tissues tested, Gdf11 was highest in normal adult mouse kidney. Expression was increased acutely after 5/6 nephrectomy, ischemia-reperfusion injury,...
The objective of this study was to define the prognostic significance of hospital surgical volume on outcomes for pediatric neuroblastoma and Wilms tumor.The Florida Cancer Data System was examined for all pediatric patients treated between 1981 and 2004.Of the 869 patients with neuroblastoma identified, 463 were treated at 5 high-volume centers (HVC) and 406 were treated at 61 low-volume centers...
To evaluate the scientific impact of presentations at the annual meetings of the Society of University Surgeons (SUS) and the Association for Academic Surgery (AAS).All Abstracts presented at the 2002-2004 annual conferences were examined for publication rate (PR), publication citation (PC) and journal impact factor (IF).Overall, 1200 abstracts from the SUS (n = 543,45%) and AAS (n = 657,55%) were...
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