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In the wear and tear process of synovial joints, wear particles generated and released from articular cartilage within the joints have surface topography and mechanical property which can be used to reveal wear conditions. Three-dimensional (3D) particle images acquired using laser scanning confocal microscopy (LSCM) contain appropriate surface information for quantitatively characterizing the surface...
Osteoarthritis (OA) is one of the most common degenerative wear diseases of knee joints worldwide. Within knee joint articular cartilage (AC), collagen structure losing integrity is a major symptom of OA. Based on the development of laser scanning confocal microscopy (LSCM), AC images containing three-dimensional (3D) surface texture information could be obtained for quantitative analysis using numerical...
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