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A highly sensitive sandwich DNA detection method based on voltammetric detection of thionine-capped gold nanoparticle (AuNP)/reporter DNA conjugate tags on gold particle-modified screen-printed carbon electrode (SPCE) was developed. The SPCE was modified with gold particle by electrodeposition of gold on SPCE surface. The DNA sensor was prepared by self-assembly of a thiolated DNA probe on gold particle-modified...
A signal-on impedimetric electrochemical DNA (E-DNA) sensor using gold nanoparticles (AuNPs) as tag was developed for highly sensitive detection of DNA hybridization. A probe ssDNA (PDNA) was immobilized by forming an amide between the NH 2 moiety at the 5′-terminus of PDNA and the COOH group at self-assembled 11-mercaptoundecanoic acid on a gold electrode. Subsequently, AuNPs were attached...
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