Search results for: Xiao-Hong Yao

Items from 1 to 20 out of 30 results

article

Targeting AKT and CK2 represents a novel therapeutic strategy for SMO constitutive activation‐driven medulloblastoma

Yue‐Liang Yao, Yan‐Xia Wang, Fei‐Cheng Yang, Chuan Wang, more

CNS Neuroscience & Therapeutics > 28 > 7 > 1033 - 1044

Aims Sonic hedgehog subtype medulloblastoma is featured with overactivation of hedgehog pathway and can be targeted by SMO‐specific inhibitors. However, the resistance is frequently developed leading to treatment failure of SMO inhibitors. W535L mutation of SMO (SMO^W535L) is thought to be an oncogenic driver for Sonic hedgehog subtype MB and confer resistance to SMO inhibitors. The regulation network...

article

Antibacterial ability and cytocompatibility of Cu-incorporated Ni–Ti–O nanopores on NiTi alloy

Jia-Ming Zhang, Yong-Hua Sun, Ya Zhao, Yan-Lian Liu, more

Rare Metals > 2019 > 38 > 6 > 552-560

Nearly equiatomic nickel–titanium (NiTi) alloy is an ideal implant biomaterial because of its shape memory effect, superelasticity, low elastic modulus as well as other desirable properties. However, it is prone to infection because of its poor antibacterial ability. The present work incorporated Cu into Ni–Ti–O nanopores (NP–Cu) anodically grown on the NiTi alloy to enhance its antibacterial ability,...

article

ARL4C stabilized by AKT/mTOR pathway promotes the invasion of PTEN‐deficient primary human glioblastoma

Qian Chen, Hai‐Yan Weng, Xiao‐Peng Tang, Yong Lin, more

The Journal of Pathology > 247 > 2 > 266 - 278

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) deficiency in primary human glioblastoma (GBM) is associated with increased invasiveness and poor prognosis with unknown mechanisms. Therefore, how loss of PTEN promotes GBM progression remains to be elucidated. Herein, we identified that ADP‐ribosylation factor like‐4C (ARL4C) was highly expressed in PTEN‐deficient human GBM cells and...

article

Stanniocalcin-1 augments stem-like traits of glioblastoma cells through binding and activating NOTCH1

Yong Li, Zhi-Cheng He, Xiao-Ning Zhang, Qing Liu, more

Cancer Letters > 2018 > 416 > C > 66-74

Glioblastoma (GBM) is a fatal tumor and comprises heterogeneous cells in which a subpopulation with stem cell-like properties is included. Cancer cells with stem cell-like properties account for tumor initiation, drug resistance and recurrence. To identify and characterize specific factors in regulating stem-like traits is critical for GBM therapeutic. Here, we showed that Stanniocalcin-1 (STC1),...

article

Construction of a SNP-based genetic linkage map for kiwifruit using next-generation restriction-site-associated DNA sequencing (RADseq)

Chun-Yan Liu, Da-Wei Li, Ju-Hong Zhou, Qiong Zhang, more

Molecular Breeding > 2017 > 37 > 11 > 1-7

Kiwifruit is a perennial horticultural crop species of the Actinidiaceae family and has high nutritional value. For a species with a long generation time, traditional breeding and genetic improvement is predicted to take more than 20 years to obtain superior cultivars. Thus, marker-assisted selection (MAS) should be used to accelerate the breeding process. Development of a genetic linkage map and...

article

High‐mobility group box 1 released by autophagic cancer‐associated fibroblasts maintains the stemness of luminal breast cancer cells

Xi‐Long Zhao, Yong Lin, Jun Jiang, Zhuo Tang, more

The Journal of Pathology > 243 > 3 > 376 - 389

Cancer stem cells/cancer‐initiating cells (CICs) and their microenvironmental niche play a vital role in malignant tumour recurrence and metastasis. Cancer‐associated fibroblasts (CAFs) are major components of the niche of breast cancer‐initiating cells (BCICs), and their interactions may profoundly affect breast cancer progression. Autophagy has been considered to be a critical process for CIC maintenance,...

article

Effects of replacement of fish meal with fermented cottonseed meal on growth performance, body composition and haemolymph indexes of Pacific white shrimp, Litopenaeus vannamei Boone, 1931

Hong Sun, Jiang‐wu Tang, Xiao‐hong Yao, Yi‐fei Wu, more

Aquaculture Research > 47 > 8 > 2623 - 2632

A feeding trial was performed for 28 days to evaluate the effects of replacement of fish meal (FM) with fermented cottonseed meal (FCM) on growth, body composition and haemolymph indexes of juvenile Litopenaeus vannamei. Four isonitrogenous and isoenergetic diets were formulated by using FCM (96.4, 206, 317 and 417 g kg⁻¹) to substitute 25%, 50%, 75% and 100% of FM in a control diet respectively....

article

Partial substitution of fish meal with fermented cottonseed meal in juvenile black sea bream (Acanthopagrus schlegelii) diets

Hong Sun, Jiang-wu Tang, Xiao-hong Yao, Yi-fei Wu, more

Aquaculture > 2015 > 446 > C > 30-36

An 8-week experiment was carried out to investigate the effects of partial replacement of fish meal with fermented cottonseed meal (FCM) on growth performance, digestibility and body composition of black sea bream, Acanthopagrus schlegelii. Fish averaging (±SD) 8.5±0.3g were fed four isonitrogenous diets containing 0, 80, 160 and 240gkg⁻¹ FCM (FCM0, 8, 16 and 24, respectively) to replace fish meal...

article

Endothelial cells promote stem‐like phenotype of glioma cells through activating the Hedgehog pathway

Guang‐Ning Yan, Lang Yang, Yang‐Fan Lv, Yu Shi, more

The Journal of Pathology > 234 > 1 > 11 - 22

Microenvironmental regulation of cancer stem cells (CSCs) strongly influences the onset and spread of cancer. The way in which glioma cells interact with their microenvironment and acquire the phenotypes of CSCs remains elusive. We investigated how communication between vascular endothelial cells and glioma cells promoted the properties of glioma stem cells (GSCs). We observed that CD133⁺GSCs were...

article

Concentration, solubility and deposition flux of atmospheric particulate nutrients over the Yellow Sea

Jin-Hui Shi, Jing Zhang, Hui-Wang Gao, Sai-Chun Tan, more

Deep-Sea Research Part II > 2013 > 97 > Complete > 43-50

Satellite images showed that two large dust storms swept over the Yellow Sea from 31 Mach to 1 April 2007; both were accompanied by precipitation. Three to four days after the dust episodes, blooms occurred in the Yellow Sea. As an important and potential controlling factor of the bloom, nutrients in the total suspended particle (TSP) and size-segregated particle samples during the cruise campaign...

article

Contrast‐enhanced transrectal ultrasonography: Measurement of prostate cancer tumor size and correlation with radical prostatectomy specimens

Ting Yue Qi, Ya Qing Chen, Jun Jiang, Yun Kai Zhu, more

International Journal of Urology > 20 > 11 > 1085 - 1091

ObjectivesTo determine the accuracy of contrast‐enhanced transrectal ultrasonography for tumor size measurements of hypoechoic prostate cancer foci located in the peripheral zone. MethodsA total of 55 men scheduled for radical prostatectomy, with biopsy‐proven cancer in hypoechoic foci located in the peripheral zone, were consecutively enrolled in the present prospective study. Each patient underwent...

article

Effects of dietary inclusion of fermented cottonseed meal on growth, cecal microbial population, small intestinal morphology, and digestive enzyme activity of broilers

Hong Sun, Jiang-wu Tang, Xiao-hong Yao, Yi-fei Wu, more

Tropical Animal Health and Production > 2013 > 45 > 4 > 987-993

Two experiments were conducted to test the feeding value of fermented cottonseed meal (FCSM) in broilers. In experiment 1, 480 1-day-old male yellow-feathered broilers were allocated into 4 dietary treatments with 6 replicates (20 birds per replicate) to examine the effects of FCSM on the growth response of chickens. Experimental feeding was performed for 6 weeks in two phases (starter, days 0 to...

article

Utility of the transition zone index for identification of prostate cancer in Chinese men with intermediate PSA levels

Ting-yue Qi, Ya-qing Chen, Jun Jiang, Yun-kai Zhu, more

International Urology and Nephrology > 2012 > 44 > 3 > 807-815

Purpose We aimed to investigate the utility of the transition zone index (TZI) for identification of prostate cancer (PCa) in Chinese men with prostate-specific antigen (PSA) levels of 4–10 ng/mL. Methods In this retrospective cohort study, results of transrectal ultrasonography (TRUS)-guided biopsy were assessed in 616 consecutive Chinese men; all subjects had intermediate serum PSA levels and...

article

Chemoattractant receptors as pharmacological targets for elimination of glioma stem-like cells

Xiao-hong Yao, Ying Liu, Keqiang Chen, Wanghua Gong, more

International Immunopharmacology > 2011 > 11 > 12 > 1961-1966

Malignant tumors are thought to be initiated by a small population of cells that display stem cell properties, including the capacity of self-renewal, multipotent differentiation, initiation of tumor tissues and resistance to therapy. Cancer stem cells (CSCs) have also been identified in gliomas in which they are named as glioma stem-like cells (GSLCs), or glioma stem cells. In xenograft transplantation...

article

Embryonal tumor with abundant neuropil and true rosettes (ETANTR) with a focal amplification at chromosome 19q13.42 locus: Further evidence of two new instances in China

Yin Wang, Shu‐Guang Chu, Ji Xiong, Hai‐Xia Cheng, more

Neuropathology > 31 > 6 > 639 - 647

Recently, the term “embryonal tumor with multilayered rosettes” (ETMR), including embryonal tumor with abundant neuropil and true rosettes (ETANTR) and ependymoblastoma (EBL) as a distinct tumor entity, has become an important topic of discussion for neuropathologists since the discovery of a unique genomic alteration in 2009. Here, we contribute two new East Asian instances of ETANTR in a 29‐month‐old...

article

Cigarette smoke‐induced skeletal muscle atrophy is associated with up‐regulation of USP‐19 via p38 and ERK MAPKs

Qian Liu, Wei‐Guo Xu, Yong Luo, Feng‐Feng Han, more

Journal of Cellular Biochemistry > 112 > 9 > 2307 - 2316

Ubiquitin‐specific proteases (USPs) deubiquitinate ubiquitin–protein conjugates in the ubiquitin–proteasome system. Previous research shows that ubiquitin‐specific protease‐19 (USP‐19) is up‐regulated in mammalian skeletal muscle in some degradative conditions, such as including fasting, diabetes, dexamethasone treatment, and cancer, and its function is associated with muscle atrophy. However, it...

article

The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell‐mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling

Yi‐fang Ping, Xiao‐hong Yao, Jian‐yong Jiang, Lin‐tao Zhao, more

The Journal of Pathology > 224 > 3 > 344 - 354

Chemokines and their receptors are actively involved in inflammation, immune responses, and cancer development. Here we report the detection of CD133⁺ glioma stem‐like cells (GSCs) co‐expressing a chemokine receptor CXCR4 in human primary glioma tissues. These GSCs were located in areas adjacent to tumour vascular capillaries, suggesting an association between GSCs and tumour angiogenesis. To test...

article

Contribution of cancer stem cells to tumor vasculogenic mimicry

Xiao-hong Yao, Yi-fang Ping, Xiu-wu Bian

Protein & Cell > 2011 > 2 > 4 > 266-272

Vasculogenic mimicry (VM), a newly-defined pattern of tumor blood supply, provides a special passage without endothelial cells and is conspicuously different from angiogenesis and vasculogenesis. The biological features of the tumor cells that form VM remain unknown. Cancer stem cells (CSCs) are believed to be tumor-initiating cells, capable of self-renewal and multipotent differentiation, which resemble...

article

Human malignant glioma cells expressing functional formylpeptide receptor recruit endothelial progenitor cells for neovascularization

Cheng-ping Xu, Hua-rong Zhang, Fei-lan Chen, Xiao-hong Yao, more

International Immunopharmacology > 2010 > 10 > 12 > 1602-1607

Endothelial progenitor cells (EPCs) are involved in tumor neovascularization with undefined mechanisms. In this study, we explored the role of formylpeptide receptor, a G protein-coupled receptor, expressed by human malignant glioma cells in neovascularization of malignant glioma. EPCs were isolated from human umbilical cord blood and their migratory capability and tubulogenesis induced by the supernatant...

article

Spontaneous Interspecific Hybridization and Patterns of Pollen Dispersal in Ex Situ Populations of a Tree Species (Sinojackia xylocarpa) that is Extinct in the Wild

JIN‐JU ZHANG, QI‐GANG YE, XIAO‐HONG YAO, HONG‐WEN HUANG

Conservation Biology > 24 > 1 > 246 - 255

Abstract: For endangered plants interspecific hybridization occurring in ex situ collections may lead to failure of reintroduction actions. We used Sinojackia xylocarpa, a well documented Chinese endemic species that is extinct in the wild, as a model case to address this concern. We used paternity analyses to assess the spontaneous hybridization and patterns of pollen flow between S. xylocarpa and its congener species, S. rehderiana, in conserved populations in Wuhan Botanic Garden. Interspecific hybridization events were detected in seven out of eight maternal trees of S. xylocarpa, and an average of 32.7% seeds collected from maternal trees of S. xylocarpa were hybrids. The paternity of 93 out of 249 seedlings from S. xylocarpa assigned to S. rehderiana provided convincing evidence that spontaneous interspecific hybridization occurred extensively in the living garden collection we studied. Different patterns of pollen dispersal (predominantly short‐distance vs. long‐distance pollination) were observed between intra‐ and interspecific hybridization events in the garden. Pollen dispersal within the ex situ populations was not restricted by distance, as evidenced by a lack of significant correlations between the average effective pollen dispersal distance (δ) and the geographic distances (d1 and d2) between maternal and paternal trees. The interspecific pollen‐dispersal distance ranged from 10 to 620.1 m (mean 294.4 m). Such extensive hybridization in ex situ collections could jeopardize the genetic integrity of endangered species and irrevocably contaminate the gene pool if such hybrids are used for reintroduction and restoration. We recommend strongly that measures be taken to minimize the genetic risks of this kind of hybridization, including establishing buffer zones in ex situ collections, manipulating flowering phenology, testing seed lots before use in reintroduction programs, and controlling pollination for seed purity....

Publication date

Last 3 years (1)

Close

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

From:

To:
Set your own date range

INFONA - science communication portal

Search results for: Xiao-Hong Yao

Targeting AKT and CK2 represents a novel therapeutic strategy for SMO constitutive activation‐driven medulloblastoma

Antibacterial ability and cytocompatibility of Cu-incorporated Ni–Ti–O nanopores on NiTi alloy

ARL4C stabilized by AKT/mTOR pathway promotes the invasion of PTEN‐deficient primary human glioblastoma

Stanniocalcin-1 augments stem-like traits of glioblastoma cells through binding and activating NOTCH1

Construction of a SNP-based genetic linkage map for kiwifruit using next-generation restriction-site-associated DNA sequencing (RADseq)

High‐mobility group box 1 released by autophagic cancer‐associated fibroblasts maintains the stemness of luminal breast cancer cells

Effects of replacement of fish meal with fermented cottonseed meal on growth performance, body composition and haemolymph indexes of Pacific white shrimp, Litopenaeus vannamei Boone, 1931

Partial substitution of fish meal with fermented cottonseed meal in juvenile black sea bream (Acanthopagrus schlegelii) diets

Endothelial cells promote stem‐like phenotype of glioma cells through activating the Hedgehog pathway

Concentration, solubility and deposition flux of atmospheric particulate nutrients over the Yellow Sea

Contrast‐enhanced transrectal ultrasonography: Measurement of prostate cancer tumor size and correlation with radical prostatectomy specimens

Effects of dietary inclusion of fermented cottonseed meal on growth, cecal microbial population, small intestinal morphology, and digestive enzyme activity of broilers

Utility of the transition zone index for identification of prostate cancer in Chinese men with intermediate PSA levels

Chemoattractant receptors as pharmacological targets for elimination of glioma stem-like cells

Embryonal tumor with abundant neuropil and true rosettes (ETANTR) with a focal amplification at chromosome 19q13.42 locus: Further evidence of two new instances in China

Cigarette smoke‐induced skeletal muscle atrophy is associated with up‐regulation of USP‐19 via p38 and ERK MAPKs

The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell‐mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling

Contribution of cancer stem cells to tumor vasculogenic mimicry

Human malignant glioma cells expressing functional formylpeptide receptor recruit endothelial progenitor cells for neovascularization

Spontaneous Interspecific Hybridization and Patterns of Pollen Dispersal in Ex Situ Populations of a Tree Species (Sinojackia xylocarpa) that is Extinct in the Wild

Filter options

Publication date

Publication language

Keywords

Data set

Journal

INFONA - science communication portal

Search results for: Xiao-Hong Yao

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Publication language

Keywords

Data set

Journal

Reporting an error / abuse

Sending the report failed

Accessibility options