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Viruses confiscate cellular components of the ubiquitin‐proteasome system (UPS) to facilitate many aspects of the infectious cycle. The 26S proteasome is an ATP‐dependent, multisubunit proteolytic machine present in all eukaryotic cells. The proteasome executes the controlled degradation of functional proteins, as well as the hydrolysis of aberrantly folded polypeptides. There is growing evidence...
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