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This is an empirical paper that measures and interprets changes in intercity relations at the global scale in the period 2000-2008. We draw on the network model devised by the Globalization and World Cities (GaWC) research group to measure global connectivities for 132 cities across the world in 2000 and 2008. A range of statistical techniques is used to explore changing connectivities at the city...
An application specific integrated circuit (ASIC) for body sensor network (BSN) was presented in this paper. Dedicated for low power wireless BSN-on-chip, the ASIC consists of reconfigurable analogue front-end (AFE) block, a 12-bit analogue-to-digital converter (ADC), a low power 32-bit RISC CPU ARM7TDMI, a scalable Fast Fourier Transform (FFT), a wireless power management unit (PMU) with battery...
The planned failure and recovery is largely overlooked in the traditional service recovery literature. The purpose of this study is to establish a process-by-outcome framework suitable to gain the understanding of the impacts of critical factors on customers' satisfaction in the planned failure. These are achieved by proposing a theoretical classification framework using the content analysis method...
Heat shock protein 90 (HSP90) and human epidermal growth factor receptor 2 protein (HER2) are involved in several signal pathways for cancer cell proliferation. We focused on these two hallmarkers to design the dual-targeted inhibitors for cancer therapy. The comparative molecular field analysis (CoMFA) and pharmacophore analysis were employed for generating the predictive models. According the leave-one...
In this investigation, the CoMFA and CoMSIA in the three-dimensional quantitative structure-activity relationship (3D-QSAR) studies were implemented to search for the pharmacophore features in each target receptor. QSAR pharmacophores hypothesis models were made from a series of ligands by their activity values. Besides, we made use of the docking strategy between the structures of each PPARs subtype...
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