Wyniki wyszukiwania dla: H. Rosner

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Management of dysnatremias with continuous renal replacement therapy

Lenar T. Yessayan, Balazs Szamosfalvi, Mitchell H. Rosner

Seminars in Dialysis > 34 > 6 > 472 - 479

Disorders of serum sodium concentration are common in critically ill patients who may have concomitant acute kidney injury, chronic kidney disease, or end‐stage kidney disease. Many of these patients may require customized serum sodium level management with dialysis which, if not strictly controlled, can lead to significant complications. Thus, controlled correction of the serum sodium level is necessary...

artykuł

Distant organ dysfunction in acute kidney injury

Faeq Husain‐Syed, Mitchell H. Rosner, Claudio Ronco

Acta Physiologica > 228 > 2 > n/a - n/a

Acute kidney injury (AKI) is a common complication in critically ill patients and it is associated with increased morbidity and mortality. Epidemiological and clinical data show that AKI is linked to a wide range of distant organ injuries, with the lungs, heart, liver, and intestines representing the most clinically relevant affected organs. This distant organ injury during AKI predisposes patients...

artykuł

Drugs in Development for Acute Kidney Injury

Matthew Hulse, Mitchell H. Rosner

Drugs > 2019 > 79 > 8 > 811-821

The care of patients with acute kidney injury (AKI) has been limited due to the lack of effective therapeutics that can either prevent AKI during high-risk situations or treat AKI once established. A revolution in the scientific understanding of the pathogenesis of AKI has led to the identification of potential therapeutic targets. These targets include pathways involved in inflammation, cellular...

artykuł

Gut–kidney crosstalk in septic acute kidney injury

Jingxiao Zhang, Ghada Ankawi, Jian Sun, Kumar Digvijay, więcej

Critical Care > 2018 > 22 > 1 > 1-8

Sepsis is the leading cause of acute kidney injury (AKI) in the intensive care unit (ICU). Septic AKI is a complex and multifactorial process that is incompletely understood. During sepsis, the disruption of the mucus membrane barrier, a shift in intestinal microbial flora, and microbial translocation may lead to systemic inflammation, which further alters host immune and metabolic homeostasis. This...

artykuł

Preoperative Renal Functional Reserve Predicts Risk of Acute Kidney Injury After Cardiac Operation

Faeq Husain-Syed, Fiorenza Ferrari, Aashish Sharma, Tommaso Hinna Danesi, więcej

The Annals of Thoracic Surgery > 2018 > 105 > 4 > 1094-1101

Although acute kidney injury (AKI) frequently complicates cardiac operations, methods to determine AKI risk in patients without underlying kidney disease are lacking. Renal functional reserve (RFR) can be used to measure the capacity of the kidney to increase glomerular filtration rate under conditions of physiologic stress and may serve as a functional marker that assesses susceptibility to injury...

artykuł

Mass Enhancements and Band Shifts in Strongly Hole-Overdoped Fe-Based Pnictide Superconductors: KFe₂As₂ and CsFe₂As₂

S.-L. Drechsler, H. Rosner, V. Grinenko, S. Aswartham, więcej

Journal of Superconductivity and Novel Magnetism > 2018 > 31 > 3 > 777-783

The interplay of high- and low-energy mass renormalizations with band shifts reflected by the positions of van Hove singularities (VHS) in the normal-state spectrum of the most strongly hole-overdoped correlated AFe₂As₂ (A122) with A=K, Cs is discussed phenomenologically from ARPES data and band-structure (GGA) calculations with full spin-orbit coupling. The big increase of the Sommerfeld coefficient...

artykuł

Drug-Induced Kidney Injury in the Elderly

Sana Khan, Valentina Loi, Mitchell H. Rosner

Drugs & Aging > 2017 > 34 > 10 > 729-741

The incidence of acute kidney injury in the elderly has grown over the past decade. One of the primary drivers is drug-induced nephrotoxicity, which is the result of a combination of the unique susceptibilities to kidney injury and the increased use of medications in the elderly population. Specific drug classes are associated with increased rates of kidney injury including agents that block the renin...

artykuł

Influenza and the patient with end-stage renal disease

Brendan T. Bowman, Mitchell H. Rosner

Journal of Nephrology > 2018 > 31 > 2 > 225-230

Influenza is a commonly encountered and serious pathogen. Patients with end-stage renal disease are more susceptible to serious morbidity and mortality associated with influenza infection. Proper management of patients includes: vaccination, monitoring for symptoms and isolation of potentially infected patients as well as appropriate antiviral therapies. In some cases of exposure, chemoprophylaxis...

artykuł

Have biomarkers failed in acute kidney injury? We are not sure

John R. Prowle, Mitchell H. Rosner

Intensive Care Medicine > 2017 > 43 > 6 > 890-892

For contrasting viewpoints, please go to doi: 10.1007/s00134-017-4759-3 and doi: 10.1007/s00134-017-4792-2 .

artykuł

Melting and solidification of lead nanoparticles embedded in Aluminium-Gallium matrices

M. Peterlechner, A. Moros, H. Rösner, S. Lazar, więcej

Acta Materialia > 2017 > 128 > C > 284-291

Analyzing the impact of the host matrix on the melting/solidification of embedded Pb nanoparticles, various Ga concentrations (0, 1, 3 and 6 at.%) were added to the Al matrix within the solid solution regime to modify the mismatch between matrix and nanoparticles by expanding the host lattice. Using transmission electron microscopy and differential scanning calorimetry, a strong impact of an atomically...

artykuł

Recent advances in CKD and ESRD: A literature update

Tushar Chopra, Mitchell H. Rosner

Hemodialysis International > 21 > 1 > 11 - 18

The past year has seen interesting publications in the fields of chronic kidney disease and end stage renal disease. This review highlights some of these important papers and places their findings in the context of clinical care.

artykuł

Sodium and Volume Disorders in Advanced Chronic Kidney Disease

Sana Khan, Matteo Floris, Antonello Pani, Mitchell H. Rosner

Advances in Chronic Kidney Disease > 2016 > 23 > 4 > 240-246

The kidney has a remarkable ability to modulate sodium and water excretion to maintain homeostasis despite a widely varying dietary intake. However, as glomerular filtration rate falls to less than 30 mL/min, this ability can be compromised leading to an increased risk for disorders of serum sodium and extracellular volume. In all cases, these disorders are associated with an increased rate of morbidity...

artykuł

Tolvaptan and Neurocognitive Function in Mild to Moderate Chronic Hyponatremia: A Randomized Trial (INSIGHT)

Joseph G. Verbalis, Howard Ellison, Mary Hobart, Holly Krasa, więcej

American Journal of Kidney Diseases > 2016 > 67 > 6 > 893-901

This trial assessed the effect of tolvaptan on cognition, gait, and postural stability in adult patients with mild to moderate asymptomatic hyponatremia.Phase 3b, multicenter, randomized, double-blind, placebo-controlled, parallel-group pilot study.57 men and women 50 years or older with chronic asymptomatic euvolemic or hypervolemic hyponatremia (serum sodium concentration >120-<135 mEq/L)...

rozdział

Thermographic Materials Characterization

H. Rösner, U. Netzelmann, J. Hoffmann, W. Karpen, więcej

Springer Series in Materials Science > Nondestructive Materials Characterization > 246-285

Thermal techniques are attractive for materials characterization. They provide sophisticated contrast mechanisms and fast, non-contact investigation of large inspection areas. Recent progress in the development of infrared cameras is the key for a wide variety of new applications. In particular, active thermal techniques provide useful information about thermal properties and related quantities as...

rozdział

Degradation of Aircraft Structures

N. Meyendorf, D. Eylon, G. S. Frankel, J. Hoffmann, więcej

Springer Series in Materials Science > Nondestructive Materials Characterization > 1-25

Maintenance and reliability of aircraft is a major safety concern and economical factor. Many civilian and military aircraft have been in service for 35 years or more. Aircrafts that were originally designed for a service life of 20 years are currently considered for life extensions of up to 80 years. The cost of corrosion and fatigue related maintenance on these aging structures has increased dramatically...

rozdział

Superconducting rare earth transition metal borocarbides

H. Rosner, S.-L. Drechsler, S.V. Shulga, K. Koeprnik, więcej

Advances in Solid State Physics > Advances in Solid State Physics 40 > 713-728

We present a overivew of the present knowledge of the electronic structure of selected properties of quaternary intermetallic rare earth transition metal borocarbides and related boronitride compounds. The calculated highly anisotropic Fermi surfaces exhibit clear similarities such as nested regions but also significant distinctions. Electrons from the nested parts of the Fermi surface affect several...

artykuł

Nanostructuring of Ba₈Ga₁₆Ge₃₀ clathrates by sol–gel‐calcination/chemical‐reduction route

V. Pacheco, H. Görlitz, M. Wagner‐Reetz, D. Kasinathan, więcej

physica status solidi (a) > 213 > 3 > 774 - 783

Nanoparticles (NPs) of Ba₈Ga₁₆Ge₃₀ clathrate‐I were synthetized via sol–gel‐calcination/chemical‐reduction route. A solution of the metallic cations was used to prepare an acryl‐amid‐based gel. The gel is dried and calcined to obtain nanocrystalline powders of precursor oxides. The oxides are reduced by reacting with CaH₂ to produce the clathrate, which is embedded in a CaO matrix. CaO is removed...

artykuł

Is Postevent Intravenous Hydration an Appropriate Service at Endurance Competitions?

Martin D. Hoffman, Tamara Hew-Butler, William O. Roberts, Ian R. Rogers, więcej

Wilderness & Environmental Medicine > 2016 > 27 > 1 > 7-9

rozdział

An Overview of Renal Physiology

Mitchell H. Rosner

Springer Specialist Surgery Series > Practical Urology: Essential Principles and Practice > Basic Sciences In Urology > 105-114

The kidney is responsible for varied and critical functions that maintain homeostasis (this can be seen in Table 7.1, which demonstrates the excretory capacity of the kidney). These functions include maintaining the volume and composition of the extracellular fluid (despite drastic and variable difference in daily intake), removal of toxic waste products (such as the end-products of metabolism such...

artykuł

To zbyt ludzkie. Czy, gdyby to było możliwe, chcielibyśmy żyć wiecznie?

H. Rosner

Świat Nauki > 2016 > 10

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