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The integration of functional proteins in the phospholipid bilayer is one of the most crucial features of biological membrane architecture. Phospholipid–protein interactions play an important role in the functions of bounded proteins in the phospholipid membrane. When the phospholipid–protein interactions occur, the protein structure tends to alter, which can result in a change in the isoelectric...
A variety of biochemical and physical properties of proteins are regulated by calcium ion (Ca 2+ ) binding with varying specificity and affinity. Calcium ion binding can adjust the phospholipid–protein interactions through changing the properties of phospholipid membrane. As an attractive detection technique, whole column imaging detection (WCID) coupled to capillary isoelectric focusing (cIEF)...
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