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The adult mammalian kidney is preceded developmentally by 2 primitive kidneys. We determine whether apoptosis is involved in the regression of these primitive organs and document its temporospatial characteristics. Timed pregnant rats were sacrificed at 11 to 16 days of gestation inclusively. The fetuses were histologically examined to determine the timing and pattern of apoptosis in the primitive...
Traditional theories of cloacal embryogenesis assume that the urorectal septum fuses with the cloacal membrane before the anal membrane disintegrates. However, recent observations in humans and other species raise doubt about this assumption. We determined whether urorectal septum fusion occurs in rats. Rat embryos were harvested at specific times between days 11 and 16 of gestation. We evaluated...
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