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ObjectiveThe approved dose of rituximab (RTX) for rheumatoid arthritis (RA) is 2 × 1,000 mg infusions given 2 weeks apart. There is contradictory evidence regarding the effectiveness of a lower‐dose regimen (2 × 500 mg) of RTX. Our aim was to compare the efficacy and safety of low‐ and high‐dose RTX and to test the noninferiority of the low‐dose regimen.
MethodsA systematic literature review searching...
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