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The numerical simulation of a novel white-light interferometric surface plasmon resonance (WLISPR) sensor with high sensitivity and wide dynamic range is presented. It is perceived that the use of a broadband polychromatic source might effectively enable wide dynamic surface plasmon detection scheme and at the same time achieving comparable phase detection sensitivity to conventional laser-based surface...
Summary form only given. We previously demonstrated an interferometric surface plasmon resonance (SPR) biosensor design based on measuring the differential phase between the s- and p-polarization. In this presentation, we report our recent results on the development of sensor arrays achieved by analyzing interferograms generated under SPR conditions. The measurement approach has the merits of performing...
A novel design of multi-pass phase-sensitive surface plasmon resonance (SPR) biosensor is presented. The system is based on differential phase interrogation scheme incorporated to the Michelson or Fabry-Perot interferometer configuration. An intrinsic phase amplification effect is achieved by placing the SPR sensor head in the signal arm of the interferometer so that the interrogating optical beam...
We propose a novel differential phase technique for improving the performance of surface plasmon resonance (SPR) biosensor systems. Typical prism-coupled schemes use a Mach-Zehnder interferometer to analyze the phase change caused by the SPR effect. In the conventional case, since the probe beam and the reference beam are required to separate into two different optical paths, mechanical drift and...
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