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Purpose To study the effect of isoenergetic administration to adult rats of high-fat or high-fat–high-fructose diet for 2 weeks on skeletal muscle mitochondrial energetic. Methods Body and skeletal muscle composition, energy balance, plasma lipid profile and glucose tolerance were measured, together with mitochondrial functionality, oxidative stress and antioxidant defense. Results Rats fed high-fat–high-fructose...
We assessed the alterations in mitochondrial function in skeletal muscle that were elicited by short-term high-fat feeding in sedentary rats.Two groups of rats were pair-fed for 1 wk and received a low-fat or high-fat diet. Body composition, energy balance, and glucose homeostasis were measured. Mitochondrial mass, oxidative capacity, and energetic efficiency as well as parameters of oxidative stress...
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