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Intervertebral Disc Degeneration
A biomimetic peptide (OAFF) binds to C‐X‐C motif chemokine receptor 1 (CXCR1) and forms fibrous networks on nucleus pulposus stem cells (NPSCs) for mimicking extracellular matrix formation, which induces NPSCs quiescence and ultimately overcomes obstacle in intradiscal injection therapy. More details can be found in article number 2300578 by Lei Wang, Bo Huang, and...
Maintaining quiescence of stem cells is a potential way to decrease cell nutrition demand for restoring the organization. Herein, a biomimetic peptide to maintain quiescence of stem cells through C‐X‐C motif chemokine ligand 8 (CXCL8)‐C‐X‐C motif chemokine receptor 1 (CXCR1) pathway against intervertebral disc degeneration (IVDD) is developed. First, it is confirmed that quiescence can be induced...
Sustained oral uncoupler 2,4‐dinitrophenol (DNP) administration exerts prominent anti‐obesity effects, but the adipose tissue off‐target disadvantage leads to systemic adverse effects. A novel non‐cardiotoxicity DNP delivery method using a biocompatible microneedles patch containing the amphiphilic tetradecanoic acid‐DNP ester (TADNP) is described, which is synthesized via esterification on the phenolic...
Considering the significant application of acetylene (C2H2) in the manufacturing and petrochemical industries, the selective capture of impurity carbon dioxide (CO2) is a crucial task and an enduring challenge. Here, a flexible metal–organic framework (Zn‐DPNA) accompanied by a conformation change of the Me2NH2+ ions in the framework is reported. The solvate‐free framework provides a stepped adsorption...
Near‐infrared‐II (NIR‐II) imaging has shown great potential for monitoring the pathological progression and deep tissue imaging but is limited to present unmet NIR‐II agent. Present fluorophores show a promising prospect for NIR‐II imaging, but brightness and photostability are still highly challenging during real‐time monitoring. In this work, atom‐engineered NIR‐II Au24Cd1 clusters with ultrahigh...
Metal selenides are considered as one of the most promising anode materials for Na‐ion batteries owing to high specific capacity and relatively higher electronic conductivity compared with metal sulfides or oxides. However, such anodes still suffer from huge volume change upon repeated Na+ insertion/extraction processes and simultaneously undergo severe shuttle effect of polyselenides, thus leading...
Thrombotic diseases have a high rate of mortality and disability, and pose a serious threat to global public health. Currently, most thrombolytic drugs especially protein drugs have a short blood‐circulation time, resulting in low thrombolytic efficiency. Therefore, a platelet membrane (Pm) cloaked nanotube (NT‐RGD/Pm) biomimetic delivery system with enhanced thrombolytic efficiency is designed. Nanotubes...
Platelet Membrane Cloaked Nanotubes
In article number 2205260, Fazheng Ren, Yuan Li, and co‐workers developed nature‐inspired platelet membrane‐cloaked nanotubes conjugated with targeting arginine glycine‐aspartic peptide and thrombolytic agent urokinase to achieve clot‐targeting and penetrating. This biomimetic carrier showed a promising effect in improving the thrombolytic efficiency in vitro and...
Solar‐driven production of hydrogen peroxide (H2O2), as an important industrial chemical oxidant with an extensive range of applications, from oxygen reduction is a sustainable alternative to mainstream anthraquinone oxidation and direct hydrogenation of dioxygen methods. The efficiency of solar to hydrogen peroxide over semiconductor‐based photocatalysts is still largely limited by the narrow light...
Two‐dimensional (2D) lamellar membranes have attracted increasing attention for efficient water purification. However, the low water‐permeability, structural failure in aqua and high production cost have significantly restricted their practical large‐scale applications. Inspired by the structures of glomerular filtration barrier (GFB) and nacre, a high‐performance biomimic membrane via supramolecular‐mediated...
Ultraviolet detection is of great significance due to its wide applications in the missile tracking, flame detecting, pollution monitoring, and so on. The nonlayered semiconductor γ‐Bi2O3 is a promising candidate toward high‐performance UV detection due to the wide bandgap, excellent light sensitivity, environmental stability, nontoxic and elemental abundance properties. However, controllable preparation...
2D materials have received considerable research interest owing to their abundant material systems and remarkable properties. Among them, 2D group VB transition metal chalcogenides (GVTMCs) stand out as emerging 2D metallic materials and significantly broaden the research scope of 2D materials. 2D GVTMCs have great advantages in electrical transport, 2D magnetism, charge density wave, sensing, catalysis,...
In article number 2000228, Luying Li, Tianyou Zhai, and co‐workers prepare large‐size BiOCl flakes with thickness down to a monolayer via salt‐assisted chemical vapor deposition. The 2D BiOCl photodetectors exhibit high responsivity throughout the solar‐blind range at room and high temperatures. The success in fabrication of atomically thin BiOCl photodetectors opens opportunities for their potential...
2D wide‐bandgap semiconductors demonstrate great potential in fabricating solar‐blind ultraviolet (SBUV) photodetectors. However, the low responsivity of 2D solar‐blind photodetectors still limits their practical applications. Here, high‐responsivity solar‐blind photodetectors are achieved based on 2D bismuth oxychloride (BiOCl) flakes. The 2D BiOCl photodetectors exhibit a responsivity up to 35.7...
In article number 1802995, Guoqiang Li and co‐workers demonstrate a 2D GaN with wellcontrolled lattice structure and bandgap on graphene/Si hetero‐structure. The bandgap for 2D GaN in P63MC and R3m structure is determined to be ≈4.65 and ≈4.18 eV, respectively. The 2D GaN shows a great potential for the development of deep ultraviolet devices.
2D group‐III nitride materials have shown a great promise for applications in optoelectronic devices thanks to their thickness‐dependent properties. However, the epitaxial growth of 2D group‐III nitrides remains a challenge. In this work, epitaxial growth of 2D GaN with well‐controlled lattice structures and bandgaps is achieved by plasma‐enhanced metal organic chemical vapor deposition via effective...
Alloy anodes have shown great potential for next‐generation lithium‐ion batteries (LIBs) and sodium‐ion batteries (SIBs). However, these applications are still limited by inherent huge volume changes and sluggish kinetics. To overcome such limitations, graphene‐protected 3D Sb‐based anodes grown on conductive substrate are designed and fabricated by a facile electrostatic‐assembling and subsequent...
Graphene‐protected 3D Sb‐based anodes are designed and fabricated by Y. Yu and co‐workers using a facile electrostatic assembly and confinement replacement method. On page 6026, in this fabrication, commercial nickel foam is used as both a 3D growth substrate and as a reductant for converting Sb3+ to Sb. When evaluated as binder‐free anodes for Li‐ion and sodium‐ion batteries, the obtained 3D electrodes...
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