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The next generation genome sequencing problem with short (long) reads is an emerging field in numerous scientific and big data research domains. However, data sizes and ease of access for scientific researchers are growing and most current methodologies rely on one acceleration approach and so cannot meet the requirements imposed by explosive data scales and complexities. In this paper, we propose...
To compare the newly determined sequences against the subject sequences stored in the databases is a critical job in the bioinformatics. Fortunately, recent survey reports that the state-of-the-art aligners are already fast enough to handle the ultra amount of short sequence reads in the reasonable time. However, for aligning the long sequence reads (> 400bp) generated by the next generation sequencing...
Bioinformatics is an emerging field with seemingly limitless possibilities for advances in numerous scientific research and applications domains. In this paper, we summaries the explosive cutting-edge acceleration engines for the emerging short read mapping problems. What's more, we propose a novel Cloud based web service solution to the short read mapping problem in DNA sequencing, which greatly...
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