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The advent of new chronic hepatitis C virus (HCV) therapies requires characterization of patients in order to predict adequate treatment. A good candidate marker is Programmed Cell Death-1 (PD-1) which is involved in progression of HCV infection. The aim of this study was to analyse the effect of several single nucleotide polymorphisms of PD-1 gene and several previously associated factors (IL28B...
Wnt/β-catenin activation is seen during early liver regeneration (LR) observed as stabilization and translocation to the nucleus followed by an overall decrease. However, β-catenin continues to be in hepatocyte nucleus and membrane, secondary to its increased gene expression at 6–72h.In the present study, we examined the effect of ablating β-catenin transcription on LR. Twelve male fisher rats were...
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