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Abstract. Common antiarrhythmic agents affect ionic membrane channels and thereby alter cellular electrical activity. Since this accounts for the proarrhythmic effects as well we tried to find new substances with different profiles of actions. A new antiarrhythmic peptide, H2N-Gly-Ala-Gly-4Hyp-Pro-Tyr-CONH2 (AAP10), was synthetized using the Fmoc-strategy. This peptide was analyzed for its electrophysiological...
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