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A method for analyzing the structural alterations in Asn or Asp residues was developed by using the peptides related to neuronal conformational diseases, i.e., the prion protein (PrP)106–126 and the Alzheimer's amyloid β (Aβ) protein6–28. The alterations were analyzed by reversed‐phase (RP) HPLC, because the peptides containing the structurally altered residues were diastereoisomers of each other,...
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