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Experimental evidence reveals that phytoestrogens have many targets through which they inhibit growth of breast cancer cells. These targets include cyclins, inhibitors of cyclin-dependent kinases (p21/p27), the tumour-suppressor gene p53, and pro-apoptotic and anti-apoptotic genes including Bax and Blc-2. This review covers the experimental evidence for mechanisms through which isoflavones and resveratrol...
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