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Background
The gold standard for the identification of Philadelphia (Ph)‐like acute lymphoblastic leukemia (ALL) patients is gene expression profiling. Because of its diverse nature, its identification is extremely difficult and expensive. On the genomic and proteomic landscape of Ph‐like ALL patients, there is a paucity of published literature from developing countries.
Methods
The authors used...
Background
The Breast Health Initiative (BHI) was launched to demonstrate a scalable model to improve access to early diagnosis and treatment of breast cancer.
Methods
A package of evidence‐based interventions was codesigned and implemented with the stakeholders, as part of the national noncommunicable disease program, through the existing primary health care system. Data from the first 18 months...
Background
Breast cancer is the most common cancer among women in India. Jhpiego, a not‐for‐profit health organization, is providing technical assistance for developing an evidence‐based model of breast health care in the states of Uttar Pradesh and Jharkhand in India.
Methods
A situational assessment of breast health care services using validated tools was conducted in the 2 states.
Results...
BACKGROUND
Central nervous system Langerhans cell histiocytosis (CNS‐LCH) brain involvement may include mass lesions and/or a neurodegenerative disease (LCH‐ND) of unknown etiology. The goal of this study was to define the mechanisms of pathogenesis that drive CNS‐LCH.
METHODS
Cerebrospinal fluid (CSF) biomarkers including CSF proteins and extracellular BRAFV600E DNA were analyzed in CSF from patients...
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