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Base-base correlation (BBC), as a novel sequence feature, reflects genome information structure. BBC has been applied to distinguish various functional regions of genomes. Meanwhile, as a genomic signature, BBC is used to compare sequences from different species. The database based on BBC feature has been constructed to search for similar sequences. It has been found that BBC carries a strong phylogenetic...
Immunobiosensors were developed for detection of Escherichia coli O157:H7 based on the surface immobilization of monoclone antibodies onto indium tin oxide (ITO) electrodes. The immobilization of antibodies onto ITO chips was carried out by silanization. The effects of epoxysilane monolayer, the antibody layer on the electrochemical properties of the electrode, and the combined target bacteria were...
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