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Depression in astronauts is one of the consequences of space flight effects, negatively impacting their work performances. Unfortunately, the underlying molecular mechanisms in space flight‐induced depression are still unknown; however, various neuropsychiatric disorders reported that overexpressed NR2B‐PSD‐95‐nNOS complex in the brain triggers various pathological pathways, and inhibiting NR2B‐PSD‐95‐nNOS...
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