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Artesunate (ART), derived from a common traditional Chinese medicine, has beeen used an antimalarial for several years. In this study, the effect and mechanism of ART on anti‐human cervical cancer cells was examined. The level of prostaglandin E2 (PGE2) and the population of CD4+CD25+Foxp3 regulatory T cells (Treg) in peripheral blood were detected by flow cytometry. In vivo antitumor activity was...
Brain‐derived neurotrophic factor (BDNF) plays a critical role in the pathogenesis of neuropathic pain, but its regulation of BDNF release is not fully understood. To further understand the regulation of BDNF release, the microglial cell line, C8‐D1A (microglia, in short), were cultured as a model. The levels of BDNF were determined by enzyme‐linked immunoassay. Apoptotic microglia were assessed by...
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