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A new method has been developed for the preparation of amine-terminated surfaces with a highly cross-linked Si–O–Si network sub-layer on gold substrates. Biotinylation of the amine-terminated layers thus obtained can be easily accomplished by the use of an activated biotin reagent. Each step of the synthetic process was monitored by Fourier transformed infrared reflection adsorption spectroscopy (FT-IRRAS)...
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