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Quinolines have a weighty effect as anticancer agents and 1,4‐DHPs have demonstrated efficacy as anticancer agents in several studies, as well. New hybrid models of symmetric and asymmetric 1,4‐DHPs and pyridines linked at C3 of 2‐chloroquinoline as a new anticancer scaffold, were designed and synthesized. Hantszch 1,4‐DHPs method was adopted for chemical synthesis. MTT assay was performed for the...
New quinolines substituted with various heterocycles and chalcone moieties were synthesized and evaluated as antitumor agents. All the synthesized compounds were in vitro screened against 60 human cancer cell lines. Compound 13 showed the highest cytotoxicity toward 58 cell lines, exhibiting distinct growth inhibition values (GI50) against the majority of them, including SR, HL‐60 (TB) strains (leukemia),...
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