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B-cell epitopes play an important role for developing synthetic peptide vaccines and inducing antibody responses. Applying biological experiments for epitope identification is time consuming and demands a lot of experimental resources. Nevertheless, it is important yet challenging task for designing a computer-aided B-cell linear epitope prediction system with high precision rates. In this paper,...
We have recently found that the computation time of homology-based subcellular localization can be substantially reduced by aligning profiles up to the cleavage site positions of signal peptides, mitochondrial targeting peptides, and chloro-plast transit peptides [1]. While the method can reduce the profile alignment time by as much as 20 folds, it cannot reduce the computation time spent on creating...
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