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Fluorescent semiconductor quantum dots (QDs) are frequently used in conjunction with biological molecules in a wide variety of applications. A negative 30-nm shift in QD emission has been observed upon binding CdSe QDs to DNA origami, a large scaffolded double-stranded DNA molecule. This paper effectively explains the observed emission shift by modeling the effect of the electric field generated by...
Quantum-dot (QD) based nanosensors can be used to detect a wide range of molecules. This study examined a nanosensor comprised of thrombin binding aptamer (TBA) with 700NC InGaP QD on the 5 terminus and an Au nanoparticle quencher on the 3 terminus. Both and bind to TBA, resulting in a conformational change that brings the Au quencher closer to the QD...
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