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Cartilage is one of the most important tissues in mammalian growth and is classified into three types: hyaline, fibro, and elastic. To illustrate its potential as a clinical diagnostic tool, nonlinear optical microscopy (NLOM) was applied to simultaneously investigate images and spectra from three different types of rat cartilage. High-resolution images were obtained using the two-photon excited fluorescence...
Assessment of tumor invasion depth prior to making therapeutic decisions in colorectal carcinoma is crucial for both the patient and the physician. In this paper, multiphoton microscopy (MPM) was used to simultaneously label freely image loose areolar connective tissue in the submucosa and intramuscular septa in the muscularis propria to perform assessment of colorectal carcinoma invasion depth. The...
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