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The core–shell biodegradable microspheres loading human serum albumin (HSA) and paracetamol were fabricated with a hydrophilic alginic acid (ALG) shell and a hydrophobic poly(lactic-co-glycolic acid) (PLGA) core. The two model drugs, HSA and paracetamol, were entrapped in the shell and core, respectively. Theses microspheres were characterized in terms of morphology, mean size and size distribution,...
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