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Background
Impaired cerebrovascular reactivity (CVR) plays an important role in the pathophysiology of white matter hyperintensities (WMHs). The pathogenesis of CVR in the development of WMH‐related cognitive impairment (CI) remains poorly understood.
Purpose
To detect the CVR status in WMH subjects with/without CI by using a resting‐state blood oxygenation level‐dependent (BOLD) approach and to...
The prevalence of white matter hyperintensities (WMH) rises dramatically with aging. Both the progression of WMH and changing patterns of default mode network (DMN) have been proven to be closely associated with cognitive function. The present study hypothesized that changes in functional connectivity and structural connectivity of DMN contributed to WMH related cognitive impairment.A total of 116...
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