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Joint mobility decreases in the elderly and in diabetics, this process is thought to be caused by accumulation of advanced‐glycation end products (AGEs). Here, we aimed to elucidate the role of AGEs in joint contracture formation in rat knees. Rats were injected with ribose or saline into the knees twice weekly for 8 weeks. Pentosidine (AGE) levels were measured in the knee‐joint tissues. After serial...
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