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Multi-Harmonic Phase Analysis (MHPA) has been developed for heart failure prognosis by reliably measuring left-ventricular (LV) dyssynchrony from conventional gated single photon emission tomography (GSPECT) myocardial perfusion imaging (MPI). Although MHPA has been evaluated in multiple clinical studies, its accuracy can be limited under highly noisy conditions. The purpose of this study is to develop...
Multi-Harmonic Phase Analysis (MHPA) has been developed to quantify left-ventricular (LV) mechanical dyssynchrony with gated single photon emission tomography (SPECT) myocardial perfusion imaging (MPI). Although MHPA has shown promising clinical results, it needs to be optimized technically. The purpose of this study is to develop a tool to simulate LV mechanical dyssynchrony in gated SPECT MPI using...
Circular trajectories are commonly used in cone-beam (CB) CT. Insufficient data measurement in such a geometry induces CB artifacts in CT images. Development of an efficient algorithm to reduce this problem remains a major challenge. A backprojection-based method is proposed here. Each CB projection is analyzed in radon space via Grangeat's formula. Assuming the CB projection is taken from a parallel...
An X-ray system with a large area detector has high scatter-to-primary ratios (SPRs), which result in severe artifacts in reconstructed computed tomography (CT) images. A scatter correction algorithm is introduced that provides effective scatter correction but does not require additional patient exposure. The key hypothesis of the algorithm is that the high-frequency components of the X-ray spatial...
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