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Older people are at increased risk of non-union after spinal fusion, but little is known about the factors determining the quality of the fusion mass in this patient group. The aim of this study was to investigate fusion mass bone quality after uninstrumented spinal fusion and to evaluate if it could be improved by additional direct current (DC) electrical stimulation. A multicenter RCT compared 40...
BACKGROUND CONTEXT: The biological factors determining a successful spinal fusion have not yet been fully determined.PURPOSE: To determine the influence of graft cell vigor on fusion rate and fusion mass using in vitro osteoblast proliferation as a predictor.STUDY DESIGN: Animal study randomizing to posterolateral fusion with autograft with or without pedicle-screw instrumentation.PATIENT SAMPLE:...
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