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We report a novel method to regenerate a biosensor surface in microfluidics. By applying a low DC voltage (0.9 V) between two electrodes, the sensing surface resets to be reusable/reconfigurable through electrodesorption of short-chain self assembled monolayers (SAMs). This method is free from electrolysis (HER (hydrogen evolution reaction)) and electrode oxidation (peel-off). Real-time SPR (surface...
We report a novel method to regenerate a biosensor surface in microfluidics. By applying a low DC voltage (0.9 V) between two electrodes submerged in phosphate buffered saline, the sensing surface resets to be reusable and reconfigurable; streptavidin-bound COOH–SAM completely desorbs and CH3-terminated self-assembled monolayer (SAM) forms on the sensing surface to capture the subsequent target molecule,...
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