Search results for: Le Yang

Items from 1 to 20 out of 390 results

article

Room‐Temperature Out‐of‐Plane Ferroelectricity and Resistance Switching Based on 2D Bi₂O₂Se

Lei Tang, Le‐Yang Dang, Mengjiao Han, Shengnan Li, more

Advanced Functional Materials > 34 > 40 > n/a - n/a

Although 2D Bi₂O₂Se plays an important role in the electronics and optoelectronics based on its in‐plane property, its out‐of‐plane electrical transport behavior remains unclear, especially in fabricating vertical devices with high integration density for novel functionality. Here, a solution‐processed method is developed to prepare 2D Bi₂O₂Se with mass production (e.g., hundreds of milliliter scale)...

article

Inside Back Cover: A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity (Angew. Chem. Int. Ed. 40/2024)

Yue Wu, Yafen Chen, Thomas P. Corner, Yu Nakashima, more

Angewandte Chemie International Edition > 63 > 40 > n/a - n/a

The tyrosine‐flip pocket in FIH (cover image centre), crucial for the development of selective FIH inhibitors, is studied in the Research Article (e202410438) by Christopher Schofield, Xiaojin Zhang et al. A ligand binding induced tyrosine flip enables development of the potent and selective FIH inhibitor ZG‐2291, a useful probe for the physiological functions of FIH; FIH inhibition by small molecules...

article

A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity

Yue Wu, Yafen Chen, Thomas P. Corner, Yu Nakashima, more

Angewandte Chemie International Edition > 63 > 40 > n/a - n/a

In animals, limiting oxygen upregulates the hypoxia‐inducible factor (HIF) and promotes a metabolic shift towards glycolysis. Factor inhibiting HIF (FIH) is an asparaginyl hydroxylase that regulates HIF function by reducing its interaction with histone acetyl transferases. HIF levels are negatively regulated by the HIF prolyl hydroxylases (PHDs) which, like FIH, are 2‐oxoglutarate (2OG) oxygenases...

article

Innenrücktitelbild: A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity (Angew. Chem. 40/2024)

Yue Wu, Yafen Chen, Thomas P. Corner, Yu Nakashima, more

Angewandte Chemie > 136 > 40 > n/a - n/a

article

A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity

Yue Wu, Yafen Chen, Thomas P. Corner, Yu Nakashima, more

Angewandte Chemie > 136 > 40 > n/a - n/a

article

Conscious but not thinking—Mind‐blanks during visuomotor tracking: An fMRI study of endogenous attention lapses

Mohamed H. Zaky, Reza Shoorangiz, Govinda R. Poudel, Le Yang, more

Human Brain Mapping > 45 > 11 > n/a - n/a

Attention lapses (ALs) are complete lapses of responsiveness in which performance is briefly but completely disrupted and during which, as opposed to microsleeps, the eyes remain open. Although the phenomenon of ALs has been investigated by behavioural and physiological means, the underlying cause of an AL has largely remained elusive. This study aimed to investigate the underlying physiological substrates...

article

Properties of polylactic acid/gelatin/acetyl tributyl citrate blend materials

Ruhui He, Yao Tao, Zhu Luo, Le Yang, more

Journal of Applied Polymer Science > 141 > 29 > n/a - n/a

The inherent brittleness and high cost of polylactic acid (PLA) hinder its further application. Developing low‐cost, flexible, and biodegradable gelatin (GEL)‐modified PLA is a way to broaden the application prospects of PLA applications. Acetyl tributyl citrate (ATBC) was added to overcome the process difficulty of PLA/GEL melt blending and toughening the blends. Maleic anhydride (MAH) grafted PLA...

article

Influence of aramid fibers modified by glycidyl polyhedral silsesquioxane assisted with supercritical carbon dioxide on the properties of aramid fiber‐reinforced styrene butadiene rubber composites

Yang Li, Caiwen Shi, Xiaoli Pan, Le Yang, more

Polymer International > 73 > 6 > 454 - 463

The weak interfacial adhesion of aramid fibers (AFs) in rubber composites can be improved by modifying their surface structure. Herein, modified AFs with a high grafting rate were prepared by modification using glycidyl polyhedral silsesquioxane (POSS) assisted with supercritical carbon dioxide (scCO₂). X‐ray photoelectron spectroscopy confirmed the chemical bonding between AFs and glycidyl POSS....

article

Fabrication and investigation of graphene‐loaded triiron tetraoxide/silicone‐rubber electromagnetic shielding composites based on static magnetic‐field–induced orientation

Jiaxing Guo, Qin Zhou, Jikai Xie, Hong Yin, more

Polymer Composites > 45 > 7 > 6588 - 6605

Graphene‐loaded triiron tetraoxide/silicone‐rubber composites containing highly loaded graphene‐loaded Fe₃O₄ (Fe₃O₄@RGO) particles were fabricated using static magnetic field‐induced alignment. The Fe₃O₄@RGO particles were characterized through Fourier transform infrared, x‐ray diffraction, SEM, and XPS analyses. Subsequently, the influence of added material and the strength of the magnetic field...

article

New construction strategies of carbon‐based composites for flexible electromagnetic interference shielding films

Shan Liu, Min He, Daohai Zhang, Chengtao Gao, more

Polymer Composites > 45 > 7 > 5804 - 5826

Due to the quick growth of portable/wearable devices and electronics, the development of high efficiency flexible electromagnetic interference shielding films is a hot research topic. This work discusses the latest advances in flexible carbon‐based electromagnetic interference shielding films, such as constructing desirable structures, combining with magnetic constituents, and filling with polymer...

article

Efficient Homolytic Cleavage of H₂O₂ on Hydroxyl‐Enriched Spinel CuFe₂O₄ with Dual Lewis Acid Sites

Lei Tian, Zi‐Jun Tang, Le‐Yang Hao, Ting Dai, more

Angewandte Chemie International Edition > 63 > 17 > n/a - n/a

Traditional H₂O₂ cleavage mediated by macroscopic electron transfer (MET) not only has low utilization of H₂O₂, but also sacrifices the stability of catalysts. We present a non‐redox hydroxyl‐enriched spinel (CuFe₂O₄) catalyst with dual Lewis acid sites to realize the homolytic cleavage of H₂O₂. The results of systematic experiments, in situ characterizations, and theoretical calculations confirm...

article

Efficient Homolytic Cleavage of H₂O₂ on Hydroxyl‐Enriched Spinel CuFe₂O₄ with Dual Lewis Acid Sites

Lei Tian, Zi‐Jun Tang, Le‐Yang Hao, Ting Dai, more

Angewandte Chemie > 136 > 17 > n/a - n/a

article

Efficient Carrier Transport in 2D Bi₂O₂Se/CsBi₃I₁₀ Perovskite Heterojunction Enables Highly‐Sensitive Broadband Photodetection

Le‐Yang Dang, Zhan Wei, Jing Guo, Tian‐Hao Cui, more

Small > 20 > 15 > n/a - n/a

2D Bi₂O₂Se has recently garnered significant attention in the electronics and optoelectronics fields due to its remarkable photosensitivity, broad spectral absorption, and excellent long‐term environmental stability. However, the development of integrated Bi₂O₂Se photodetector with high performance and low‐power consumption is limited by material synthesis method and the inherent high carrier concentration...

article

Construction of alumina framework with a sponge template toward highly thermally conductive epoxy composites

Xian Wu, Wei Liu, Le Yang, Chun Zhang

Polymer Engineering & Science > 64 > 4 > 1812 - 1821

Ceramic‐based polymer composites are commonly utilized as thermal management materials due to their high thermal conductivity and electrical insulation properties. One efficient method to enhance the thermal conductivity of these composites is by constructing a three‐dimensional thermal conductive network within the polymer matrix. In this study, alumina was coated onto the surface of polyurethane...

article

Co‐Encapsulating Enzymes and Carbon Dots in Metal–Organic Frameworks for Highly Stable and Sensitive Touch‐Based Sweat Sensors

Xin Ting Zheng, Melisa Wei Ning Leoi, Yong Yu, Sherwin Chong Li Tan, more

Advanced Functional Materials > 34 > 10 > n/a - n/a

Wearable metabolite sensors are often limited by easily denaturable enzymes that only allow short‐duration monitoring. Although encapsulating enzymes in metal–organic frameworks (MOFs) shows promise of long‐term enzyme protection, it is typically accompanied by significantly decreased activity due to increased diffusion barrier, steric hindrance for enzyme‐substrate binding, and poor enzyme‐electronic...

article

Corner‐Sharing Tetrahedrally Coordinated W‐V Dual Active Sites on Cu₂V₂O₇ for Photoelectrochemical Water Oxidation

Zheng‐Yi Huang, Yi‐Ying Chen, Le‐Yang Hao, Ying‐Jie Hua, more

Small > 20 > 8 > n/a - n/a

The sluggish four‐electron oxygen evolving reaction is one of the key limitations of photoelectrochemical water decomposition. Optimizing the binding of active sites to oxygen in water and promoting the conversion of *O to *OOH are the key to enhancing oxygen evolution reaction. In this work, W‐doped Cu₂V₂O₇ (CVO) constructs corner‐sharing tetrahedrally coordinated W‐V dual active sites to induce...

article

Evaluation of the key ingredient from the main production areas of Phellodendri Amurensis Cortex using ultra‐high‐performance liquid chromatography‐quadrupole time‐of‐flight tandem mass spectrometry and ultra‐high‐performance liquid chromatography coupled to triple‐quadrupole mass spectrometry

Yuran Sun, Qiqi Zhao, Heng Fang, Hui Sun, more

Journal of Separation Science > 47 > 4 > n/a - n/a

Phellodendri Amurensis Cortex (PAC) is a medicinal herb that has been generally used to treat diarrhea and jaundice. In order to comprehensively evaluate the PAC in the main production areas quality, a qualitative and quantitative method with highly effective, sensitive, and reliable was developed. The chemical compositions of PAC were analyzed, and fingerprints were established by ultra‐high‐performance...

article

Highly Stretchable and Conductive MXene‐Encapsulated Liquid Metal Hydrogels for Bioinspired Self‐Sensing Soft Actuators

Shaoshuai Ma, Pan Xue, Cristian Valenzuela, Xuan Zhang, more

Advanced Functional Materials > 34 > 7 > n/a - n/a

Advanced sensation and actuation abilities of various living organisms in nature have inspired researchers to design bioinspired self‐sensing soft actuators. However, the majority of conventional soft actuators primarily possess actuation capabilities while lacking a real‐time sensing signal feedback. Here, a promising strategy is reported to develop highly stretchable and conductive hydrogels for...

article

Chemical profiling of Simiao pill and quantification of main effective constituents in it by ultra‐high‐performance liquid chromatography coupled with Q Exactive Orbitrap and triple quadrupole mass spectrometry

Le Yang, Ye Sun, Shuyun Wei, Hao Wen, more

Journal of Separation Science > 47 > 1 > n/a - n/a

Simiao pill is one of the most commonly used prescriptions in traditional Chinese medicine for the treatment of hyperuricemia and gout. However, methods based on more accurate and comprehensive qualitative and quantitative analyses of the active ingredients are not yet perfect due to limited methodology. This not only hinders the elucidation of the pharmacological mechanism of Simiao pill, but also...

article

Blocking Accretion Enables Dimension Reduction of Metal‐Organic Framework for Photocatalytic Performance

Zejin Wang, Rui Ding, Xiaoke Li, Jie Zhang, more

Small > 19 > 52 > n/a - n/a

The evolution and formation process of two‐dimensional metal‐organic frameworks (MOFs) primarily arise from the anisotropic growth of crystals, leading to variations in photocatalytic performance. It is crucial to achieve a synergistic combination of anisotropic electron transfer direction and dimension reduction strategies. In this study, a novel approach that effectively blocks crystal growth accretion...

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INFONA - science communication portal

Search results for: Le Yang

Room‐Temperature Out‐of‐Plane Ferroelectricity and Resistance Switching Based on 2D Bi₂O₂Se

Inside Back Cover: A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity (Angew. Chem. Int. Ed. 40/2024)

A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity

Innenrücktitelbild: A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity (Angew. Chem. 40/2024)

A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity

Conscious but not thinking—Mind‐blanks during visuomotor tracking: An fMRI study of endogenous attention lapses

Properties of polylactic acid/gelatin/acetyl tributyl citrate blend materials

Influence of aramid fibers modified by glycidyl polyhedral silsesquioxane assisted with supercritical carbon dioxide on the properties of aramid fiber‐reinforced styrene butadiene rubber composites

Fabrication and investigation of graphene‐loaded triiron tetraoxide/silicone‐rubber electromagnetic shielding composites based on static magnetic‐field–induced orientation

New construction strategies of carbon‐based composites for flexible electromagnetic interference shielding films

Efficient Homolytic Cleavage of H₂O₂ on Hydroxyl‐Enriched Spinel CuFe₂O₄ with Dual Lewis Acid Sites

Efficient Homolytic Cleavage of H₂O₂ on Hydroxyl‐Enriched Spinel CuFe₂O₄ with Dual Lewis Acid Sites

Efficient Carrier Transport in 2D Bi₂O₂Se/CsBi₃I₁₀ Perovskite Heterojunction Enables Highly‐Sensitive Broadband Photodetection

Construction of alumina framework with a sponge template toward highly thermally conductive epoxy composites

Co‐Encapsulating Enzymes and Carbon Dots in Metal–Organic Frameworks for Highly Stable and Sensitive Touch‐Based Sweat Sensors

Corner‐Sharing Tetrahedrally Coordinated W‐V Dual Active Sites on Cu₂V₂O₇ for Photoelectrochemical Water Oxidation

Highly Stretchable and Conductive MXene‐Encapsulated Liquid Metal Hydrogels for Bioinspired Self‐Sensing Soft Actuators

Chemical profiling of Simiao pill and quantification of main effective constituents in it by ultra‐high‐performance liquid chromatography coupled with Q Exactive Orbitrap and triple quadrupole mass spectrometry

Blocking Accretion Enables Dimension Reduction of Metal‐Organic Framework for Photocatalytic Performance

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