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Cadmium (Cd 2+ ) is a major nephrotoxic environmental pollutant, affecting mostly proximal convoluted tubule (PCT) cells of the mammalian kidney, while conditionally Cd 2+ could also elicit protective responses with great variety and variability in different systems. The present study was designed to evaluate the molecular mechanism of Cd 2+ toxicity on human PCT derived Renal...
Cadmium (Cd) is one of the ubiquitous environmental pollutants and is responsible for various organ pathophysiology including hepatic disorders. It is extremely toxic even in low concentrations and bioaccumulate in organisms. The present study has been carried out to investigate the cytoprotective role of arjunolic acid (AA), a tri terpenoid saponin, against Cd induced oxidative impairment and cell...
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