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Silver nanoparticles (AgNPs) are useful to a wide range of consumer’s and medical products, due to their antimicrobial and anti-inflammatory activities. AgNPs have been used to prevent the microbial colonization, therefore decreasing the risk of infection, on implantable devices, tumor prostheses, bone cement and surgical instruments. However, the putative toxicity of AgNPs to bone cells is still...
Surface coating of silver nanoparticles may influence their toxicity, in a way yet to decipher. In this study, human keratinocytes (HaCaT cells) were exposed for 24 and 48h to well-characterized 30nm AgNPs coated either with citrate (Cit30 AgNPs) or with poly(ethylene glycol) (PEG30 AgNPs), and assessed for cell viability, reactive oxygen species (ROS), cytokine release, apoptosis and cell cycle dynamics...
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