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Objective
To explore alterations in fecal short‐chain fatty acids (SCFA) and gut microbiota in patients with diarrhea‐predominant irritable bowel disease (IBS‐D) and their relationships with clinical manifestations.
Methods
We recruited 162 patients with IBS‐D and 66 healthy controls (HC). Their manifestations and psychological status were evaluated using the IBS severity scoring system and the...
ObjectiveWe aimed to investigate the role of mast cell in stress‐induced barrier dysfunction in the esophagus and its possible pathway involved using mast cell‐deficient (Ws/Ws) rats.
MethodsWs/Ws rats and normal (+/+) rats were submitted to chronic restraint stress (CRS) 2 h/day for 7 days. Tissues were obtained from distal esophagus. Mast cells were counted under Alcian blue‐safranin O stain. Activation...
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