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What's known on the subject? and What does the study add?Insulin‐like growth factor mRNA‐binding protein 3 (IMP3) is an oncofetal protein found to be re‐expressed in a series of human cancers including bladder cancer. In vitro analyses showed an invasion and proliferation promoting effect for IMP3. Further in vitro studies suggested that IMP3 is able to bind to the mRNAs of CD44 and insulin‐like growth...
Study Type – Therapy (case series) Level of Evidence 4What’s known on the subject? and What does the study add? Recent data suggest that MMP‐7 is critically involved in metastasis formation. In accordance, we formerly found significantly elevated MMP‐7 tissue expression and serum concentration in samples of patients with metastatic bladder cancer and observed an independent correlation between MMP‐7...
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