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The family of human Nek (NIMA Related Kinase) kinases currently contains 11 members. We have identified Nek8 as a new member of the Nek kinase family. For many of the Nek family members, primary tumor expression data and function have been limited. However, all of the Nek family proteins share considerable homology with the Never In Mitosis, gene A (NIMA) kinase from the filamentous fungus Aspergillus...
The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. We report the isolation and characterization of genomic and cDNA clones encoding avian CCAAT/enhancer-binding protein-γ (C/EBPγ). A partial cDNA clone for a C/EBP-related gene was previously identified by expression library screening for proteins binding the A1 CCAAT/enhancer motif...
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