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Detecting and analyzing pathogenic bacteria in an effective and reliable manner is crucial for the diagnosis of acute bacterial infection and initial antibiotic therapy. However, the precise labeling and analysis of bacteria at the single‐bacterium level are a technical challenge but very important to reveal important details about the heterogeneity of cells and responds to environment. This study...
In article number 1603418, Baojun Li and co‐workers develop a single‐bacterium labeling and analysis method. By optical connecting of a single bacterium with single upconversion nanoparticles which emits green light using an optical cotrapping method, single bacterium can be labeled and moved to designated locations in 3D, and the signal from the labeled single bacterium can be detected in real time...
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