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Vestibular schwannomas (VS) frequently express high levels of activated AKT. Small-molecule inhibitors of AKT signalling may have therapeutic potential in suppressing the growth of benign VS and malignant schwannomas.Primary VS and Schwann cells, human malignant schwannoma HMS-97 cells and mouse Nf2 –/– Schwann cells and schwannoma cells were prepared to investigate the growth inhibitory and...
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