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Gender dysphoria is discomfort living as a male or as a female. When sufficiently distressing it leads to the request for ‘sex change’. The age range of patients is adolescence to mid-life, and three-quarters are born male. Clinical practice should proceed from reversible steps to the more irreversible. Clothing change and name change precede hormone administration, which may precede surgery. The...
Gender identity development as male or female, a fundamental feature of personhood, remains enigmatic. More puzzling is when it contradicts the person's birth sex as male or female. Attempts to understand that discrepancy, exemplified by transsexualism, harness knowledge from research on prenatal sex hormones, genetics, brain function and influences of socialization.
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