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Interleukin‐21 (IL‐21) participates in tissue damage in various immune‐mediated diseases. Its role in the pathogenesis of chronic active hepatitis B (CAHB) has not been clarified. The frequency of circulating IL‐21+ T cells and the levels of serum and intrahepatic IL‐21 have been characterized in 70 CAHB patients, 32 inactive carrier (IC), 18 chronic hepatitis C (CHC) and 20 healthy controls (HC)...
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