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Three new C-15-isobutyryl 16-norphragmalin-type limonoids, chukvelutins D–F (1–3), were isolated from the stem bark of Chukrasia tabularis var. velutina. Their structures were established on the basis of detailed spectroscopic analysis. Compound 1 possessed a ketonic isobutyryl C-15 substitution previously unreported in phragmalin-type limonoids. Compounds 2 and 3 showed moderate anti-inflammatory...
Velutabularins A–J, ten novel phragmalin-type limonoids, were isolated from the stem bark of Chukrasia tabularis var. velutina. In structures of 1–6, the tetrahydrofuran ring from dehydration of OH-15 and OH-17, ring C and 13/14/18-cyclopropanyl moiety formed an unprecedented 8-oxatricyclo[4,3,1 1,6 ]decane. Compounds 7–10 are derivates of 1–6 opening the tetrahydrofuran ring. All of these...
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