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PCK3145 is an anti-metastatic synthetic peptide with promising therapeutic efficacy against hormone-refractory prostate cancer. The characterization of the PCK3145 peptide cell surface binding/internalization mechanisms and of the receptors involved remained to be explored.[ 14 C]PCK3145 cell surface binding assays showed rapid and transient kinetic profile, that was inhibited by RGD peptides,...
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