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Extracellular matrix (ECM) is a composite material which contains a complex mixture of fibrous proteins and heteropolysaccharides, providing an important model for designing biomaterials. To mimic ECM, we fabricated 3D cell niches in chitosan hydrogel network via the layer-by-layer (LbL) molecular self-assembly method. Compression modulus of genipin-crosslinked chitosan hydrogel could be regulated...
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