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The hugely storing information ability, parallel computing ability and lower computing energy cost make DNA computing to be a perfect computing paradigm. Nowadays it has been used to solve various computationally hard problems. In order to improve its reliability and simplify operations, microfluidic chips support an effective way to realize an automatable and universal DNA computer. In this paper...
Based on its massive parallel computational power and high density storage capacity, DNA computing has been applied to various computational problems. In order to improve its reliability, reduce time and simplified operations, micro fluidic chips support an effective way to realize an automat able and universal DNA computer. In this paper we introduce micro fluidic logic operators, simple fluidic...
Based on its massive parallel computational power and high density storage capacity, DNA computing has been applied to various computational problems. In order to improve its reliability, reduce time and simplified operations, microfluidic chips support an effective way to realize an automatable and universal DNA computer. In this paper we introduce microfluidic logic operators, simple fluidic switches...
Encoding and processing information in DNA-, RNA- and other biomolecule-based devices is an important requirement for DNA based computing with potentially important applications. To make DNA computing more reliable, much work has focused on designing the good DNA sequences. However, this is a bothersome task as encoding problem is an NP problem. In this paper, a new methodology based on the IWO algorithm...
DNA encoding problem, which has been proved to be an NP hard problem, is a key problem for DNA computing, and usually solved by optimization algorithms. A new efficient genetic algorithm based on cultural algorithm for the design of DNA codewords is presented in this paper. In this hybrid optimization method, to abstract and manage the information efficiently, the conventional genetic algorithm is...
An evaluation problem of codewords for DNA computing was studied. The constraints on codewords design were discussed, five evaluation criteria: distance constraint, GC-content, continuous bases, melting temperature and free energy were presented. According to the correlation of the criteria, the combined weight method, which based on statistics principle was proposed, and then a comprehensive evaluation...
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